Zynamite- What is it?

Zynamite- What is it?

Caffeine is the world's favorite drug. No questions asked. What if told I you there was a replacement to it with FAR more benefits? Well friends let me introduce you to Zynamite!

Creators of this ingredient Neekium, their R&D and innovation team began searching for a safe and effective ingredient that could not only replace caffeine but be superior!

Nektium’s research team was led by Dr. Nigel Gericke, and involved extensive reviews of the international ethnobotanical literature, of the uses of plants in the traditions of Ayurvedic Medicine and Traditional Chinese Medicine, and reviews of Nektium’s own ethnobotanical records from European, Russian, Amazonian, and African plants.

The result: Zynamite, a specialized extract from Mango Leaves which notably showed precisely but remarkably similar activation activity to caffeine in studies of brain electrical activity.

Zynamite is a patented proprietry Mangifera indica (Mango leaves) extract ideal for boosting mental and physical energy.

Zynamite® for sport recovery

The effect on pain and recovery was studied after a 10km race followed by 100 drop jumps, demonstrating the following results:

  • Accelerated recovery of muscle performance
  • Reduced pain and muscle damage elicited by competitive exercise


Zynamite® for sports performance

Tested in repeat sprint exercise as well as exercise during simulated exhaustion (ischaemia-reperfusion model) in men and women.

  • Increased peak power output
  • Increased mean power output
  • Increased VO2max
  • Increased brain oxygenation in women
  • Increased muscle oxygen extraction
  • Decreased lactate




Zynamite delivers mental energy and also supports mental & physical aspects of sports performance. Several clinical studeis including zynamite improves both peak power output and mean power output in fatigued and exhausted men & women. That is exactly the place most athletes and even people find to need that extra push that much more.

Zynamite isn't just meant for athletes, it's meant for ANYONE. The cognitive/mental benefits you can get from zynamite is out of this world. 

Here's just a few of the benefits you can expect to have:

      • Rapid onset of mental activation
      • Faster reaction time
      • Sustained Energy
      • Increased Power & Performance
      • Accelerated Recovery
      • Reduced pain & muscle

At this point in time we are the ONLY retailer to offer Zynamite as a stand-alone ingredient thanks to our friends at AZOTH and we are VERY excited about this!

Click here for Zynamite. 

If you want to try Azoth Total Focus containing Zynamite with a small dosse of PurCaf caffeine and Rhodiola click HERE.

Peer reviewed publications


Dimpfel, W., et al. Zynamite®(Mangifera indica leaf extract) and Caffeine Act in a Synergistic Manner on Electrophysiological Parameters of Rat Central Nervous System. Food and Nutrition Sciences, 9, 502-518 (2018).

Gelabert-Rebato, M., et al. Enhancement of Exercise Performance by 48 Hours, and 15-Day Supplementation with Mangiferin and Luteolin in Men. Nutrients, 11 (2), 344 (2019).

Gelabert-Rebato, M., et al. Mangifera indica L. leaf Extract (Zynamite®) in Combination with Luteolin or Quercetin Enhances VO2peak and Peak Power Output, and Preserves Skeletal Muscle Function During Ischemia-Reperfusion in Humans. Front. Physiol. 9, 740 (2018).

Gelabert-Rebato, et al. A Single Dose of The Mango Leaf Extract Zynamite® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients, 11 (11), 2592 (2019).

Reddeman, R.A., et al. A Toxicological Evaluation of Mango Leaf Extract (Mangifera indica) Containing 60% Mangiferin. Journal of toxicology, (2019).

Martin-Rinco, M., et al. Supplementation with a Mango Leaf Extract (Zynamite®) in Combination with Quercetin Attenuates Muscle Damage and Pain and Accelerates Recovery After Strenuous Damaging Exercise. Nutrients (2020).


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  • Jesse Westover