GlucoVantage® enhances insulin sensitivity effectively as well as inhibits adipocyte (fat cell) growth. Supports a healthy blood glucose level and insulin level.
GlucoVantage® is the first commercially available brand of Dihydroberberine (DHB), a derivative of berberine, which is an alkaloid isolated from Berberis Aristata.
Berberine has been used in Chinese and Ayurvedic medicine for decades and shown to be effective on optimizing blood glucose, improving insulin sensitivity and body composition, yet despite its demonstrated efficacy, berberine is limited by poor bioavailability.
Recent evidence demonstrates that DHB displays 5-fold better intestinal absorption than berberine in animals.
DHB is a metabolite of berberine in the human body and has higher bioavailability than berberine. It’s the active form of berberine, that the gut must convert for berberine to be effectively utilized. Further, the gut microbiota is initiating this conversion from berberine to the active metabolite, DHB, and may be the reason some experience gastrointestinal (GI) distress with standard berberine.
New research is being conducted with DHB having potential synergy when co-administered with Bifidobacterium species enhancing the probiotic (as opposed to dysbiotic) nature of the gut.